In a large bowl, combine the ground chicken, egg, bread crumbs, hot sauce, garlic powder, onion powder, salt, cumin, and chili powder. Use your hands to combine fully.
Divide into 4 pieces and pat out into patties. Use your thumb to make an indentation in the center of each patty. This will help to keep the patties from shrinking and puffing up as they cook.
Place the chicken patties on a hot grill over medium heat and cook for 5 minutes. Flip and continue cooking for 5 minutes or until cooked through. Add the cheese over the top during the last minute of cooking.
To make the veggies:
While the burgers are cooking, heat a large skillet over medium high heat and melt the butter. Thinly slice the peppers and onions and add to the skillet. Sprinkle with the garlic powder, cumin, chili powder, and salt and stir to coat the peppers.
Cook, stirring often, until peppers and onions are tender crisp and slightly browned, about 8 minutes.
To assemble:
Spread the toasted buns with guacamole, top with a burger patty, and pile the vegetables over the top. Serve hot.